The Red Sox wasted a good start by Paul Byrd and ended up dropping the third game in a row to the Yankees. J-Bay scored in the first to and the third to give the Red Sox a 2-0 lead. Melky Cabrera hit a homer off of Byrd to put the Yanks on the board in the bottom of the third. The score remained 2-1 until Saito gave up a two out hit with runners on second and third to allow the Yankees to take the lead in the 6th. Bard also gave up a homer in the 8th to Mark Teixeira.
With the win the Yankees clinched the A.L. East title and are back in the playoffs after not making the post-season last year. The Rays rallied back to beat the Rangers so the Red Sox magic number dropped to two.
Red Sox Lose 4-2 BOX SCORE
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | R | H | E | |
| Red Sox | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 8 | 0 |
| Yankees | 0 | 0 | 1 | 0 | 0 | 2 | 0 | 1 | 0 | 4 | 10 | 1 |
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