| Player | Injury | Monday | Tuesday | Wednesday | Status |
| J.Addai | Neck | LIMITED | LIMITED | LIMITED | OUT |
| G.Brackett | Toe | DNP | LIMITED | FULL | QUESTIONABLE |
| D.Brown | Ankle | DNP | FULL | FULL | QUESTIONABLE |
| A.Collie | Concussion | LIMITED | LIMITED | LIMITED | OUT |
| B.Eldridge | Rib | LIMITED | FULL | FULL | QUESTIONABLE |
| D.Freeney | Rest | DNP | DNP | FULL | WILL START |
| M.Hart | Ankle | DNP | DNP | DNP | OUT |
| K.Hayden | Neck | DNP | FULL | DNP | OUT |
| C.Johnson | Back | LIMITED | FULL | FULL | QUESTIONABLE |
| R.Mathews | Back | FULL |
FULL | FULL | QUESTIONABLE |
| R.Mathis | Rest | DNP | FULL | FULL | WILL START |
| B.Sanders | Biceps | DNP | DNP | DNP | OUT |
| C.Session | Elbow | DNP | DNP | DNP | OUT |
| T.Smith | Hamstring | FULL | FULL | LIMITED | QUESTIONABLE |
| J.Tamme | Knee | DNP | DNP | LIMITED | QUESTIONABLE |
| R.Wayne | Knee | DNP | FULL | FULL | QUESTIONABLE |
***NOTES***
– CB Jerraud Powers was placed on IR this week, ending his season. With Kelvin Hayden out, CBs Justin Tryon and Jacob Lacey will start.
– Due to numerous injuries in the secondary the Colts have placed Bob Sanders on IR and signed rookie CB David Pender from the Practice Squad.
– There has been no word on the injury to Jacob Tamme, but his lack of practice time is disturbing with the already depleted receiving corps.
– There is still no timetable for the return of Clint Session to the lineup.
– RB Dominique Rhodes was signed earlier in the week to help add depth to the Colts RB corps with injury concern for Brown, and Hart out once again.
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